Sunday, September 19, 2021

Guillain-Barre is complication of Covid vaccines says U S FDA, report by Gloria Poole,RN in Springfield MO

I, Gloria Poole,Registered Nurse, artist/writer/ watched this virtual meeting with FDA: "Vaccines and related Biological products:" on youtube today at https://www.youtube.com/watch?v=WFph7-6t34M

My very brief summary of it : Guillain-Barre Syndrome [GBS] is a neurological consequence of covid vaccine and so is "thrombosis thrombocytopenia syndrome" with Janssen/ JandJ vaccine and AstroZeneca; with no prior patient history of risks, so development of complications was not predictable. "Long covid"causes brain fog and heart symptoms. VAERS is abbreviation for U S FDA/CDC"s Vaccine Adverse Event Reporting System. To report a complication of covid vaccine(s) see patient information, which has links to VAERS. Patient, family, or "health care provider" can report complications even on paper form if person does not have internet.

Teleconference with FDA on web 19Sept2021;5:24am

Then I researched it more using Google and am including some of the results to make quick reference :

Quote : "GBS is a rare condition where the body’s immune system damages nerve cells and typically presents with sensory abnormalities, muscle weakness and autonomic dysfunction, often triggered by infection, although the cause is not always identified. It usually develops over hours or days, starting in the extremities (hands and feet) before spreading to the arms and legs, typically affecting both sides. Initial symptoms include numbness, pins and needles, muscle weakness, pain, and balance and coordination problems. Severity can range from mild, transient weakness to complete paralysis. It is generally a single episode in a patient’s life."

Source:

https://www.gov.uk/government/publications/covid-19-vaccination-guillain-barre-syndrome-information-for-healthcare-professionals/information-for-healthcare-professionals-on-guillain-barre-syndrome-gbs-following-covid-19-vaccination;

On web 19 Sept 2021; 5:30am

More on topic, quote:

"Coronavirus disease 2019 (COVID-19) is still propagating a year after the start of the pandemic. Besides the complications patients face during the COVID-19 disease period, there is an accumulating body of evidence concerning the late-onset complications of COVID-19, of which autoimmune manifestations have attracted remarkable attention from the first months of the pandemic. Autoimmune hemolytic anemia, immune thrombocytopenic purpura, autoimmune thyroid diseases, Kawasaki disease, Guillain-Barre syndrome, and the detection of autoantibodies are the cues to the discovery of the potential of COVID-19 in inducing autoimmunity..."

For instance, according to previous reports on autoimmune manifestations and autoimmune-related markers in coronavirus disease 2019 (COVID-19) patients, a growing body of research has been devoted to the exploration of the association between COVID-19 infection and autoimmune conditions. Acute hemolytic anemia, macrophage activating syndrome, Kawasaki-like disease, Guillain-Barre syndrome (GBS), Miller Fisher syndrome (MFS), autoimmune thrombotic thrombocytopenic purpura, autoimmune skin manifestations, and detection of autoantibodies are some of the pieces of evidence pointing to the potential interconnection between autoimmunity and COVID-19. [footnote 7-11 ]... Infections have been known as the most important environmental trigger in the complex pathophysiology of autoimmune diseases. Different mechanisms are hypothesized to explain how infections might provoke autoimmune reactions. Epitope spreading, bystander activation, cross-reaction or molecular mimicry, and presentation of cryptic antigens are the suggested mechanisms. [footnote 13] For instance, type 1 diabetes mellitus (T1DM) as one of the most prevalent autoimmune diseases has been suggested to be associated with coxsackievirus, [footnote 14] cytomegalovirus (CMV),[ footnote 15] and enteroviruses.[footnote 16] Different types of viral infections such as hepatitis C virus (HCV), [footnote 17] CMV, [footnote 18] dengue virus,[footnote 19] and parvovirus B1920, [footnote 21] have been postulated to be associated with systemic lupus erythematosus (SLE) that represent a wide variety of autoimmune manifestations. Furthermore, multiple sclerosis (MS) has been found to be associated with Epstein-Barr virus (EBV),22 measles virus,23 Varicella-zoster virus,24 and CMV [footnote 25, 26 (Table 1)]. The aforementioned examples support the role of viral infections in the initiation of autoimmune diseases particularly in individuals with genetic susceptibility.... Clinical and laboratory findings indicate the hyperactivity of the immune system in COVID-19 cases... [discussion of how particular cells are affected is too long to quote here] Considering all the aforementioned findings regarding the immune dysregulation evidence in infected patients with COVID-19, postulating an autoimmunity process in the course of COVID-19 infection is of interest."[end quote]

from Journal of Medical Virology at https://onlinelibrary.wiley.com/doi/10.1002/jmv.27292.

19Sept2021;6:10am

Signs and Symptoms of Guillain-Barre Syndrome from World Health Organization:

Quote:

"The WHO lists the following symptoms for the Guillain-BarrĂ© syndrome:

* The first symptoms include weakness or tingling sensation, which usually start in the legs, and can spread to the arms and face.

* For some people, these symptoms can lead to paralysis of the legs, arms, or muscles in the face.

* In 20 to 30 percent of cases, the chest muscles are affected, making it hard to breathe.

*  In severe cases, the ability to speak and swallow may become affected. These cases are considered life-threatening, and affected individuals should be treated in intensive-care units.

* !!!!!!!Complications can include paralysis of the muscles that control breathing, blood infection, lung clots, or cardiac arrest and even in the best of settings, 3–5 percent of patients suffering from the syndrome die from the complications.

* The NINDS also lists difficulty with eye muscles and vision, co-ordination problems and unsteadiness, pain that can be severe, particularly at night, abnormal heart beat/rate or blood pressure, and problems with digestion and/or bladder control as probably symtpoms. It states that most people seek medical care following weakness on both sides of the body.

* Occasionally symptoms start in the upper body and move down to the legs and feet, the NINDS adds.

The global health body states that the symptoms typically last a few weeks but most people most recover fully from even the most severe case of Guillain-BarrĂ© syndrome. While some continue to experience weakness, most recover without long-term, severe neurological complications.

According to the NINDS, the types of GBS include acute inflammatory demyelinating polyneuropathy (AIDP) — the most common type in the US— acute motor axonal neuropathy (AMAN), and acute motor-sensory axonal neuropathy (AMSAN). Miller-Fisher syndrome is a rare, acquired nerve disease and a variant of GBS.

What treatment does it require?

* There is no known cure for GBS but there are treatments that can help improve symptoms of GBS and shorten the recovery time.[end quote]

Source:

* https://www.firstpost.com/health/all-about-guillain-barre-syndrome-the-autoimmune-disease-associated-with-zika-virus-infection-9791371.html;

* 19sept2021;6:20am

Also, so there is no confusion in readers, I create art and post some of it to my blogs on web. I updated some of them recently including https://gloriapoole.blogspot.com

and https://gloriapoole-paintings.blogspot.com

and https://gloria0817.blogspot.com

and https://gpoole817.blogspot.com

and https://mini-exhibition.blogspot.com.

I also post to other blogs of mine on the topics of prolife news/events and pending legislation; and politics that affects that including my:

https://prolife-nurse.blogspot.com; and other blogs also.

Posted today 19Sept 2021 at 7:40am by me Gloria Poole,Registered Nurse [retired secondary to trauma], artist in all mediums; from my own private apartment in Springfield Missouri using my own equipment I bought and the wired internet that comes into my apartment. This blog of mine [and only mine] is a PUBLIC HEALTH information service provided by me Gloria Poole, RN, as a Registered Nurse, to help educate the public on public health issues in language they will understand better.